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This study was a comparison between salbutamol plus 17-alpha HP and magnesium sulfate for the prevention of PTL. One hundred and four of patients admitted for prevention of PTL were randomly assigned to two groups having 52 patients in each group. One group was given 5 mg salbutamol in 500 mL of 5% D/S, at a dose of 10 mu min(-1) to a maximum of 45 mu min(-1) until contraction ceased or side effects started, then we initiated soon, 250 mg of 17-alpha HP, it was administrated by weekly intramuscular injection and was continued until 36 weeks 6 days or delivery. Another group was given 10 g magnesium sulfate intramuscular then 5 g every four hours until contraction ceased or side effects started. Successful tocolysis achieved similar in each group. Mean uterine contraction ceasing time in group I was 5.4 h and in group II, 16.8 h. The delay in the delivery till 37 weeks of gestation in group II was lower …