作者
Milena Deptuła, Małgorzata Zawrzykraj, Justyna Sawicka, Adrianna Banach-Kopeć, Robert Tylingo, Michał Pikuła
发表日期
2023/11/1
来源
Biomedicine & Pharmacotherapy
卷号
167
页码范围
115416
出版商
Elsevier Masson
简介
Hydrogels are three-dimensional polymer networks with hydrophilic properties. The modifiable properties of hydrogels and the structure resembling living tissue allow their versatile application. Therefore, increasing attention is focused on the use of hydrogels as bioinks for three-dimensional (3D) printing in tissue engineering. Bioprinting involves the fabrication of complex structures from several types of materials, cells, and bioactive compounds. Stem cells (SC), such as mesenchymal stromal cells (MSCs) are frequently employed in 3D constructs. SCs have desirable biological properties such as the ability to differentiate into various types of tissue and high proliferative capacity. Encapsulating SCs in 3D hydrogel constructs enhances their reparative abilities and improves the likelihood of reaching target tissues. In addition, created constructs can simulate the tissue environment and mimic biological signals …
引用总数
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M Deptuła, M Zawrzykraj, J Sawicka, A Banach-Kopeć… - Biomedicine & Pharmacotherapy, 2023