作者
Ellemarije Altena, Jennifer R Ramautar, Ysbrand D Van Der Werf, Eus JW Van Someren
发表日期
2010/1/1
图书
Progress in brain research
卷号
185
页码范围
181-205
出版商
Elsevier
简介
The cognitive changes that occur with ageing are usually referred to as ‘age-related cognitive decline’. The most pronounced changes may be found in the executive functions that require integrity of the prefrontal cortical circuitry. With age, sleep also changes profoundly, with more sleep fragmentation, earlier awakenings and less slow wave sleep as its main features. Interestingly, experimental sleep deprivation studies in healthy young adults showed a particularly consistent effect on executive functions, suggesting that sleep problems might contribute to the cognitive changes accompanying older age. We here investigate this possibility by reviewing reports on age-related and insomnia-related changes in cognition and brain function and structure, as found in studies investigating subjective complaints, objective functioning in everyday life, neuropsychological assessment, psychometry, structural and functional …
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E Altena, JR Ramautar, YD Van Der Werf… - Progress in brain research, 2010