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Patients with uncontrolled open-angle glaucoma were treated with argon laser to the trabecular meshwork. These patients were divided into six groups. Each group of eyes had a slightly different technique of argon laser therapy. Except for one group, there was an adequate pressure lowering effect at the longest follow-up (−18 to −28%). Since the worst complication of argon laser trabeculoplasty is the immediate elevation in intraocular pressure with subsequent worsening of the field and/or disc, the immediate rise in intraocular pressure was measured and compared for each of the various techniques. In addition comparison was made when treating 180° in one eye and 360° in the other eye of 30 individuals having similar glaucomatous disease bilaterally. Little difference was noted between the two eyes.