作者
Allan Komakech, Shannon Whitmer, Jonathan Izudi, Charles Kizito, Mackline Ninsiima, Sherry R Ahirirwe, Zainah Kabami, Alex R Ario, Daniel Kadobera, Benon Kwesiga, Samuel Gidudu, Richard Migisha, Issa Makumbi, Daniel Eurien, Joshua Kayiwa, Lilian Bulage, Doreen N Gonahasa, Irene Kyamwine, Paul E Okello, Hildah T Nansikombi, Immaculate Atuhaire, Alice Asio, Sarah Elayeete, Edirisa J Nsubuga, Veronica Masanja, Stella M Migamba, Patience Mwine, Petranilla Nakamya, Rose Nampeera, Andrew Kwiringira, Rebecca Akunzirwe, Helen Nelly Naiga, Saudah K Namubiru, Brian Agaba, Jane Frances Zalwango, Marie Gorreti Zalwango, Patrick King, Brenda Nakafeero Simbwa, Robert Zavuga, Mercy Wendy Wanyana, Thomas Kiggundu, Lawrence Oonyu, Alex Ndyabakira, Mariam Komugisha, Brian Kibwika, Innocent Ssemanda, Yasin Nuwamanya, Adams Kamukama, Dorothy Aanyu, Dominic Kizza, Daniel Okello Ayen, Sophia Mulei, Stephen Balinandi, Luke Nyakarahuka, Jimmy Baluku, Jackson Kyondo, Alex Tumusiime, Dativa Aliddeki, Ben Masiira, Esther Muwanguzi, Ivan Kimuli, Daniel Bulwadda, Herbert Isabirye, Deborah Aujo, Arthur Kasambula, Solome Okware, Emmanuel Ochien, Innocent Komakech, Charles Okot, Mary Choi, Caitlin M Cossaboom, Carrie Eggers, John D Klena, Modupe O Osinubi, Katrin S Sadigh, Mary C Worrell, Amy L Boore, Trevor Shoemaker, Joel M Montgomery, Susan N Nabadda, Michael Mwanga, Allan N Muruta, Julie R Harris
发表日期
2024/5/23
期刊
BMC Infectious Diseases
卷号
24
期号
1
页码范围
520
出版商
BioMed Central
简介
Background
On 20 September 2022, Uganda declared its fifth Sudan virus disease (SVD) outbreak, culminating in 142 confirmed and 22 probable cases. The reproductive rate (R) of this outbreak was 1.25. We described persons who were exposed to the virus, became infected, and they led to the infection of an unusually high number of cases during the outbreak.
Methods
In this descriptive cross-sectional study, we defined a super-spreader person (SSP) as any person with real-time polymerase chain reaction (RT-PCR) confirmed SVD linked to the infection of ≥ 13 other persons (10-fold the outbreak R). We reviewed illness narratives for SSPs collected through interviews. Whole-genome sequencing was used to support epidemiologic linkages between cases.
Results
Two SSPs (Patient A, a 33-year-old male, and Patient B, a 26-year-old male) were identified, and linked to the infection of one probable and 50 …
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A Komakech, S Whitmer, J Izudi, C Kizito, M Ninsiima… - BMC Infectious Diseases, 2024