作者
Sally Temraz, Deborah Mukherji, Zein Al Abideen Farhat, Rami Nasr, Maya Charafeddine, Mohammed Shahait, Mohammad Rachad Wehbe, Rami Abou Ghaida, Ibrahim Abu Gheida, Ali Shamseddine
发表日期
2014/12
期刊
BMC urology
卷号
14
页码范围
1-6
出版商
BioMed Central
简介
Background
Inflammation is a critical component of tumorigenesis, and many cancers arise from sites of infection, chronic irritation, and inflammation. Inflammatory cytokines triggered by tumors alter hematologic components, including neutrophil, lymphocyte, and monocyte counts. The neutrophil-to-lymphocyte and platelet-to-lymphocyte ratios have been shown to be valuable prognostic markers in various types of cancers, including bladder cancer. Risk stratification based on clinicopathologic data is insufficient to support treatment-related choices in patients with bladder cancer. Novel prognostic markers are therefore needed. An elevated pretreatment lymphocyte-to-monocyte ratio (LMR) is reportedly associated with improved overall survival (OS) and a longer time to treatment recurrence (TTR) in some types of cancers. However, these data are lacking in patients with bladder cancer …
引用总数
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