作者
Stergios A Polyzos, Marina Κita, Zoe Efstathiadou, Pavlos Poulakos, Aristidis Slavakis, Danae Sofianou, Nikolaos Flaris, Maria Leontsini, Anargyros Kourtis, Avraam Avramidis
发表日期
2008/9
期刊
Journal of cancer research and clinical oncology
卷号
134
页码范围
953-960
出版商
Springer-Verlag
简介
Purpose
Serum thyrotropin (TSH) is a well-established growth factor for thyroid nodules and suppression of TSH concentrations by administering exogenous thyroxine may interfere with the growth of established nodules as well as the formation of new thyroid nodules. The aim of this study was to investigate whether serum TSH at presentation is a predictor of thyroid malignancy in patients with thyroid nodules.
Methods
A total of 565 patients without overt thyroid dysfunction, who presented with palpable thyroid nodule(s) between 1988 and 2004 and underwent at least one fine-needle aspiration biopsy, were retrospectively evaluated.
Results
The final diagnostic outcome was established after surgery (n = 122) or after a minimum of 1-year clinical follow-up period. Higher rates of malignancy were observed in patients …
引用总数
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SA Polyzos, M Κita, Z Efstathiadou, P Poulakos… - Journal of cancer research and clinical oncology, 2008