作者
Radomir Chabiniok, Vicky Y Wang, Myrianthi Hadjicharalambous, Liya Asner, Jack Lee, Maxime Sermesant, Ellen Kuhl, Alistair A Young, Philippe Moireau, Martyn P Nash, Dominique Chapelle, David A Nordsletten
发表日期
2016/4/6
来源
Interface focus
卷号
6
期号
2
页码范围
20150083
出版商
The Royal Society
简介
With heart and cardiovascular diseases continually challenging healthcare systems worldwide, translating basic research on cardiac (patho)physiology into clinical care is essential. Exacerbating this already extensive challenge is the complexity of the heart, relying on its hierarchical structure and function to maintain cardiovascular flow. Computational modelling has been proposed and actively pursued as a tool for accelerating research and translation. Allowing exploration of the relationships between physics, multiscale mechanisms and function, computational modelling provides a platform for improving our understanding of the heart. Further integration of experimental and clinical data through data assimilation and parameter estimation techniques is bringing computational models closer to use in routine clinical practice. This article reviews developments in computational cardiac modelling and how their …
学术搜索中的文章
R Chabiniok, VY Wang, M Hadjicharalambous, L Asner… - Interface focus, 2016