作者
Christina Ip, King Sum Luk, Vincent Lok Cheung Yuen, Lorraine Chiang, Ching Ki Chan, Kevin Ho, Mengqi Gong, Teddy Tai Loy Lee, Keith Sai Kit Leung, Leonardo Roever, George Bazoukis, Konstantinos Lampropoulos, Ka Hou Christien Li, Gary Tse, Tong Liu, International Health Informatics Study IHIS Network
发表日期
2021/12/1
来源
IJC Heart & Vasculature
卷号
37
页码范围
100887
出版商
Elsevier
简介
Objectives
Soluble suppression of tumorigenicity 2 (sST2) is a member of the interleukin-1 receptor family. It is raised in various cardiovascular diseases, but its value in predicting disease severity or mortality outcomes has been controversial. Therefore, we conducted a systematic review and meta-analysis to determine whether sST2 levels differed between survivors and non-survivors of patients with cardiovascular diseases, and whether elevated sST2 levels correlated with adverse outcomes.
Methods
PubMed and Embase were searched until 23rd June 2021 for studies that evaluated the relationship between sST2 levels and cardiovascular disease severity or mortality.
Results
A total of 707 entries were retrieved from both databases, of which 14 studies were included in the final meta-analysis. In acute heart failure, sST2 levels did not differ between survivors and non-survivors (mean difference [MD]: 24.2 ± 13.0 …
学术搜索中的文章
C Ip, KS Luk, VLC Yuen, L Chiang, CK Chan, K Ho… - IJC Heart & Vasculature, 2021