作者
Donato Lacedonia, GIOVANNA ELISIANA Carpagnano, M Aliani, R Sabato, MP Foschino Barbaro, Antonio Spanevello, M Carone, F Fanfulla
发表日期
2013/2/1
期刊
Respiratory medicine
卷号
107
期号
2
页码范围
310-316
出版商
WB Saunders
简介
BACKGROUND
OSAS and COPD are often associated with day-time hypoxemia. Overlap Syndrome (OS), the association between both diseases, increases the risk of day-time hypoxemia. The aim of this study was to investigate the mechanisms which could justify the low oxygen level and the effect of CPAP.
METHODS
We performed a retrospective analysis in all patients referred to our institutes for suspected OSAS and who also underwent spirometry and blood gas analysis during our evaluation. Thus, 720 patients were selected. According to pulmonary function test parameters they were divided into 3 groups: OSAS (N = 466,65%); OS (N = 168,23%) and COPD (N = 86,12%). In order to evaluate the differences between the three groups, ANOVA analyses were carried out, whereas a multivariate analysis was performed in order to evaluate which factors determine the diurnal PaO2. In 90 patients we also have …
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