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The retrospective study by Darvall and colleagues 1 examined the impact of frailty on mortality among patients with (non-COVID-19) pneumonia admitted for intensive care. The authors commented that clinical frailty score (CFS) alone is not useful for guiding the allocation of critical care resources because lesser degrees of frailty (CFS 5e6) were not associated with mortality. 1 Whether the findings could be extended to patients with coronavirus disease 2019 (COVID-19) is unknown. Many researchers have sought to determine if frailty predicts poor prognosis in hospitalised patients with COVID-19. We aim to summarise the available evidence from observational studies through meta-analysis regarding the association between frailty and mortality in patients with COVID-19.

We performed a comprehensive literature search in electronic databases that included PubMed, Scopus, Google Scholar, and preprint …