作者
Azizullah Beran, Mohammed Mhanna, Omar Srour, Hazem Ayesh, Omar Sajdeya, Sami Ghazaleh, Asmaa Mhanna, Dana Ghazaleh, Waleed Khokher, Aadil Maqsood, Ragheb Assaly
发表日期
2022/4/1
来源
Respiratory Care
卷号
67
期号
4
页码范围
471-479
出版商
Respiratory Care
简介
BACKGROUND
Awake prone positioning (APP) has been recently proposed as an adjunctive treatment for non-intubated coronavirus disease 2019 (COVID-19) patients requiring oxygen therapy to improve oxygenation and reduce the risk of intubation. However, the magnitude of the effect of APP on clinical outcomes in these patients remains uncertain. We performed a comparative systematic review and meta-analysis to evaluate the effectiveness of APP to improve the clinical outcomes in non-intubated subjects with COVID-19.
METHODS
The primary outcomes were the need for endotracheal intubation and mortality. The secondary outcome was hospital length of stay. Pooled risk ratio (RR) and mean difference with the corresponding 95% CI were obtained by the Mantel-Haenszel method within a random-effect model.
RESULTS
A total of 14 studies (5 randomized controlled trials [RCTs] and 9 observational …
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A Beran, M Mhanna, O Srour, H Ayesh, O Sajdeya… - Respiratory Care, 2022