作者
Alexandre Joosten, Joseph Rinehart, Philippe Van der Linden, Brenton Alexander, Christophe Penna, Jacques De Montblanc, Maxime Cannesson, Jean-Louis Vincent, Eric Vicaut, Jacques Duranteau
发表日期
2021/8/1
期刊
Anesthesiology
卷号
135
期号
2
页码范围
258-272
出版商
Lippincott Williams & Wilkins
简介
Background
Individualized hemodynamic management during surgery relies on accurate titration of vasopressors and fluids. In this context, computer systems have been developed to assist anesthesia providers in delivering these interventions. This study tested the hypothesis that computer-assisted individualized hemodynamic management could reduce intraoperative hypotension in patients undergoing intermediate- to high-risk surgery.
Methods
This single-center, parallel, two-arm, prospective randomized controlled single blinded superiority study included 38 patients undergoing abdominal or orthopedic surgery. All included patients had a radial arterial catheter inserted after anesthesia induction and connected to an uncalibrated pulse contour monitoring device. In the manually adjusted goal-directed therapy group (N = 19), the individualized hemodynamic management …
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