作者
Cole Buchanan, Collen Buchanan, Maeveen Riordan, Jessica Byrd, Margaret Schulte, Wendy M Kohrt, Amrut V Ambardekar, Larry A Allen, Gene Wolfel, Justin Lawley, Benjamin D Levine, William K Cornwell III
发表日期
2024/1/1
期刊
Heart Failure
卷号
12
期号
1
页码范围
117-129
出版商
American College of Cardiology Foundation
简介
Background
Patients with heart failure with reduced ejection fraction (HFrEF) have persistent impairments in functional capacity after continuous-flow left ventricular assist device (CF-LVAD) implantation.
Objectives
This study aims to characterize longitudinal changes in exercise hemodynamics and functional capacity among patients with HFrEF before and after CF-LVAD implantation.
Methods
Ten patients underwent 3 invasive cardiopulmonary exercise tests on upright cycle ergometry with pulmonary artery catheterization: 1) Visit 1 before CF-LVAD implantation; 2) Visit 2 after device implantation with CF-LVAD pump speed held constant at baseline speed; and 3) Visit 3 with increases in pump speed during exercise (median: 1,050 rpm [IQR: 750-1,150 rpm] and 220 rpm [IQR: 120-220 rpm] for HeartMate 3 and HeartWare VAD, respectively). Hemodynamics and direct Fick cardiac output were monitored using …
学术搜索中的文章
C Buchanan, C Buchanan, M Riordan, J Byrd… - Heart Failure, 2024