作者
Aida Andrades Valtueña, Gunnar U Neumann, Maria A Spyrou, Lyazzat Musralina, Franziska Aron, Arman Beisenov, Andrey B Belinskiy, Kirsten I Bos, Alexandra Buzhilova, Matthias Conrad, Leyla B Djansugurova, Miroslav Dobeš, Michal Ernée, Javier Fernández-Eraso, Bruno Frohlich, Mirosław Furmanek, Agata Hałuszko, Svend Hansen, Éadaoin Harney, Alina N Hiss, Alexander Hübner, Felix M Key, Elmira Khussainova, Egor Kitov, Alexandra O Kitova, Corina Knipper, Denise Kühnert, Carles Lalueza-Fox, Judith Littleton, Ken Massy, Alissa Mittnik, José Antonio Mujika-Alustiza, Iñigo Olalde, Luka Papac, Sandra Penske, Jaroslav Peška, Ron Pinhasi, David Reich, Sabine Reinhold, Raphaela Stahl, Harald Stäuble, Rezeda I Tukhbatova, Sergey Vasilyev, Elizaveta Veselovskaya, Christina Warinner, Philipp W Stockhammer, Wolfgang Haak, Johannes Krause, Alexander Herbig
发表日期
2022/4/26
期刊
Proceedings of the National Academy of Sciences
卷号
119
期号
17
页码范围
e2116722119
出版商
National Academy of Sciences
简介
The bacterial pathogen Yersinia pestis gave rise to devastating outbreaks throughout human history, and ancient DNA evidence has shown it afflicted human populations as far back as the Neolithic. Y. pestis genomes recovered from the Eurasian Late Neolithic/Early Bronze Age (LNBA) period have uncovered key evolutionary steps that led to its emergence from a Yersinia pseudotuberculosis-like progenitor; however, the number of reconstructed LNBA genomes are too few to explore its diversity during this critical period of development. Here, we present 17 Y. pestis genomes dating to 5,000 to 2,500 y BP from a wide geographic expanse across Eurasia. This increased dataset enabled us to explore correlations between temporal, geographical, and genetic distance. Our results suggest a nonflea-adapted and potentially extinct single lineage that persisted over millennia without significant parallel diversification …
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A Andrades Valtueña, GU Neumann, MA Spyrou… - Proceedings of the National Academy of Sciences, 2022