作者
Yong Sang Cho, Myoung Wha Hong, Hoon‐Jin Jeong, Seung‐Jae Lee, Young Yul Kim, Young‐Sam Cho
发表日期
2017/11
期刊
Journal of Biomedical Materials Research Part B: Applied Biomaterials
卷号
105
期号
8
页码范围
2315-2325
简介
In this study, the fabrication method was proposed for the well‐interconnected polycaprolactone/hydroxyapatite composite scaffold with exposed hydroxyapatite using modified WNM technique. To characterize well‐interconnected scaffolds in terms of hydroxyapatite exposure, several assessments were performed as follows: morphology, mechanical property, wettability, calcium ion release, and cell response assessments. The results of these assessments were compared with those of control scaffolds which were fabricated by precision extruding deposition (PED) apparatus. The control PED scaffolds have interconnected pores with nonexposed hydroxyapatite. Consequently, cell attachment of proposed WNM scaffold was improved by increased hydrophilicity and surface roughness of scaffold surface resulting from the exposure of hydroxyapatite particles and fabrication process using powders. Moreover, cell …
引用总数
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