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This work focuses on understanding the formation and oxidation of soot when adding n-butanol, an oxygenated fuel, to n-dodecane. A two-stage burner was used to characterize the oxidation of soot from different n-butanol blends, 10%, 30%, and 60 mol% in n-dodecane. The two-stage burner isolates the soot oxidation process from the formation process. Soot is formed in a first-stage premixed burner under fuel-rich conditions, while in a second stage, the soot is oxidized under slightly fuel-rich conditions. A scanning mobility particle sizer (SMPS) was used to measure the soot particle size distributions in the flame at different heights during oxidation. Results showed a decrease in particle mass concentration (g/cm³) as the fraction of n-butanol increased, which indicates the capability of n-butanol to reduce soot particle number and mass. On the other hand, the results demonstrated that the increasing n-butanol …