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Interventions to combat engagement in health risk behaviours (HRB) amongst youth produces mixed results. Engagement in HRBs continues to increase with adverse effects on health and well-being. This manuscript reports on a study that attempted to demonstrate the usefulness of Intervention Mapping (IM) in developing contextually relevant programmes with increased buy-in from stakeholders, and the potential to effect behavioural change. The present study used a modified Intervention Mapping (IM) framework that included the first five IM operational steps: 1) Needs assessment (Survey), 2) Identifying performance objectives (Concept Mapping), 3) Methods and strategies (Systematic review), 4) Programme development (Triangulation of all the components in the preceding steps) and 5) Feasibility of the designed programme (Delphi Study). The manuscript demonstrated how the framework enabled the use of multiple methodologies to develop a programme that was methodologically rigorous and empirically grounded. The focus is not on the results of the various steps, but on demonstrating how the steps were applied to facilitate programme development. Ethics clearance was obtained from the UWC Senate Research Committee and all ethics principles observed. The results demonstrate that IM is an appropriate conceptual framework for collaboration that enhances the resultant programme at various levels: theoretical/ conceptual; methodological and practical application/ intervention.