作者
Hylke H Salverda, Sophie JE Cramer, Ruben SGM Witlox, Timothy J Gale, Peter A Dargaville, Steffen C Pauws, Arjan B Te Pas
发表日期
2022/1/1
期刊
Archives of Disease in Childhood-Fetal and Neonatal Edition
卷号
107
期号
1
页码范围
20-25
出版商
BMJ Publishing Group
简介
Objective
To compare the effect of two different automated oxygen control devices on target range (TR) time and occurrence of hypoxaemic and hyperoxaemic episodes.
Design
Randomised cross-over study.
Setting
Tertiary level neonatal unit in the Netherlands.
Patients
Preterm infants (n=15) born between 24+0 and 29+6 days of gestation, receiving invasive or non-invasive respiratory support with oxygen saturation (SpO2) TR of 91%–95%. Median gestational age 26 weeks and 4 days (IQR 25 weeks 3 days–27 weeks 6 days) and postnatal age 19 (IQR 17–24) days.
Interventions
Inspired oxygen concentration was titrated by the OxyGenie controller (SLE6000 ventilator) and the CLiO2 controller (AVEA ventilator) for 24 hours each, in a random sequence, with the respiratory support mode kept constant.
Main outcome measures
Time spent within set SpO2 TR (91%–95% with supplemental oxygen and 91%–100 …
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HH Salverda, SJE Cramer, RSGM Witlox, TJ Gale… - Archives of Disease in Childhood-Fetal and Neonatal …, 2022