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Although hydrogen sulfide (H2S) is known as a toxic gas with the unpleasant smell of rotten eggs, this cannot change the fact that it exists in the human body and other biological systems. It is reported that the typical concentration of H2S in blood is in the range of 10–100 μm.[1] Clearly its presence must be connected with biological functions, for example, it has been recognized as the third gaseous signaling molecule besides nitric oxide (NO) and carbon monoxide (CO).[2] The significance of endogenously produced H2S has been validated in a number of physiological and pathological processes, such as the regulation of cell growth,[3] cardiovascular protection,[4] the stimulation of angiogenesis,[5] and antioxidative effects.[6] On the other hand, its deregulation has been correlated with the symptoms of Alzheimer s disease,[7] Down s syndrome,[8] diabetes,[9] and liver cirrhosis.[10] As a result of the huge …