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Temperature-dependent sex determination has been described in turtles, crocodilians, lizards and sphenodons. In such amniotes, sexual phenotype is determined based on the incubation temperature during embryonic development. The description of temperature-dependent sex determination has often been purely qualitative, without any statistical inference. A new statistical method describing temperature-dependent sex determination with two parameters, the pivotal temperature and the transitional range of temperature producing both sexes, has been developed. The estimates and their standard deviation are produced using maximum likelihood. This method is applied using data from the literature.