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The aim of present study was to investigate the perceived stress and quality of life among Pharm. D students at Ibn Sina National College (ISNC). The sample was surveyed electronically through (Google document) that was sent to students through the email. Pharm D students from the last three professional years were invited to participate in our study. Out of 209 eligible students, 52.6%(N= 110) completed the questionnaire. The average age of the participants was 22.3±2.5 years, 78.2%(N= 86) of which were females and 21.8%(N= 24). Students reported that they were sometimes out of control during a month period with regards to the following (with p< 0.001), they faced difficulty in successful dealing with problems. Although stress has a major role in student’s life, none of the results had a negative effect on the student’s quality of life. About 51% of pharm D students experienced negative symptoms quite often such as blue mood, despair, anxiety and depression. The male students reported lower perceived stress level than female. Perceived stress is not GPA score dependent. No Relation was found between the stress and year of study.