作者
Nicholas Aderinto, Gbolahan Olatunji, Emmanuel Kokori, Praise Fawehinmi, Abdulrahmon Moradeyo, Stephen Igwe, Rebecca Ojabo, Badrudeen Olalekan Alabi, Emmanuel Chuka Okafor, Damilola Ologbe, Ayobami Olafimihan, David B Olawade
发表日期
2024/5/10
来源
Clinical Diabetes and Endocrinology
卷号
10
期号
1
页码范围
10
出版商
BioMed Central
简介
This mini-narrative review explores the relationship between diabetes and dementia, focusing on the potential mitigating role of metformin in reducing cognitive decline among individuals with type 2 diabetes. The interplay of factors such as glycemic control, diabetic complications, and lifestyle influences characterises diabetes-related dementia. This review emphasises the significance of comprehensive diabetes management in addressing the heightened risk of dementia in this population. Methodologically, the review synthesises evidence from 23 studies retrieved through searches on PubMed, Embase, Google Scholar, and Scopus. Current evidence suggests a predominantly positive association between metformin use and a reduced risk of dementia in individuals with diabetes. However, the review shows the complex nature of these outcomes, revealing variations in results in some studies. These …
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N Aderinto, G Olatunji, E Kokori, P Fawehinmi… - Clinical Diabetes and Endocrinology, 2024