作者
Xinyu Zhou, Arun V Ravindran, Bin Qin, Cinzia Del Giovane, Qi Li, Michael Bauer, Yiyun Liu, Yiru Fang, Tricia da Silva, Yuqing Zhang, Liang Fang, Xiao Wang, Peng Xie
发表日期
2015/4/22
来源
The Journal of clinical psychiatry
卷号
76
期号
4
页码范围
3423
出版商
Physicians Postgraduate Press, Inc.
简介
Objective: To comparatively analyze the efficacy, acceptability, and tolerability of various augmentation agents in adult patients with treatment-resistant depression.
Data Sources: An electronic literature search of PubMed, EMBASE, the Cochrane Library, Web of Science, EBSCO, PsycINFO, EAGLE, and NTIS for trials published up to December 2013 was conducted. Several clinical trial registry agencies and US Food and Drug Administration reports were also reviewed. No language, publication date, or publication status restrictions were imposed.
Study Selection: Randomized controlled trials comparing 11 augmentation agents (aripiprazole, bupropion, buspirone, lamotrigine, lithium, methylphenidate, olanzapine, pindolol, quetiapine, risperidone, and thyroid hormone) with each other and with placebo for adult treatment-resistant depression were included.
Data Extraction: The proportion of patients who responded …
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X Zhou, AV Ravindran, B Qin, C Del Giovane, Q Li… - The Journal of clinical psychiatry, 2015
