作者
Massumeh Niazi, Nasrin Galehdar, Mohammad Jamshidi, Rasool Mohammadi, Alireza Moayyedkazemi
发表日期
2020/4/1
来源
Current clinical pharmacology
卷号
15
期号
1
页码范围
30-37
出版商
Bentham Science Publishers
简介
Background
Heart failure is a common medical problem in the world, which has a high prevalence in both developed and developing countries. Today, among the medications used for the heart failure treatment, there are many medications with a positive cardiac contraction effect (positive inotropic such as digital glycosides, adrenergic receptor stimulants, and phosphodiesterase inhibitors), a large number of cardiac diluents (such as Angiotensin-Converting Enzyme (ACE) inhibitor group), and a few other types of drugs whose final effects are still under review. Statins are valuable drugs that are broadly prescribed in hyperlipidemia and cardiovascular patients due to their multiple properties, such as cholesterol reduction, endothelial function improvement, antioxidative, anti-inflammatory, neovascularization, and immunomodulatory activities.
Methods
There is evidence that the therapeutic role of statins in HF, due to …
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M Niazi, N Galehdar, M Jamshidi, R Mohammadi… - Current clinical pharmacology, 2020