作者
Joseph Jonathan Lee, Jan Y Verbakel, Clare Rosemary Goyder, Thanusha Ananthakumar, Pui San Tan, Phillip James Turner, Gail Hayward, Ann Van den Bruel
发表日期
2019/6/18
期刊
Clinical Infectious Diseases
卷号
69
期号
1
页码范围
24-33
出版商
Oxford University Press
简介
Background
Point-of-care tests (POCTs) for influenza are diagnostically superior to clinical diagnosis, but their impact on patient outcomes is unclear.
Methods
A systematic review of influenza POCTs versus usual care in ambulatory care settings. Studies were identified by searching six databases and assessed using the Cochrane risk of bias tool. Estimates of risk ratios (RR), standardised mean differences, 95% confidence intervals and I2 were obtained by random effects meta-analyses. We explored heterogeneity with sensitivity analyses and meta-regression.
Results
12,928 citations were screened. Seven randomized studies (n = 4,324) and six non-randomized studies (n = 4,774) were included. Most evidence came from paediatric emergency departments. Risk of bias was moderate in randomized studies and higher in non-randomized studies. In …
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JJ Lee, JY Verbakel, CR Goyder, T Ananthakumar… - Clinical Infectious Diseases, 2019
