作者
Paola Bolle, Sabina Mastrangelo, Paolo Tucci, Maria G Evandri
发表日期
2004
期刊
Environmental and molecular mutagenesis
卷号
43
期号
2
页码范围
137-141
出版商
Wiley Subscription Services, Inc., A Wiley Company
简介
Atrazine is classified as a restricted use pesticide and it is currently included in an international revision program for re‐evaluating the human and ecological (non‐human populations) health risks associated with its release into the environment. The present study was undertaken to add new data on the genotoxic potential of atrazine using the Allium cepa chromosome aberration test. The test concentrations were based on the Maximum Contaminant Levels in water intended for human consumption set by European and US regulations. Atrazine produced a concentration‐related increase in the number of total somatic chromosome aberrations, although this increase was statistically significant (p<0.05) only at the highest test concentration (5 μg/L). Analysis of the categories of structural chromosome damage indicated that breaks were the predominant lesion induced; the percent of cells per bulb with breaks also …
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学术搜索中的文章
P Bolle, S Mastrangelo, P Tucci, MG Evandri - Environmental and molecular mutagenesis, 2004