作者
Wesley K Lefferts, Elizabeth C Lefferts, Brooks A Hibner, Kurt J Smith, Bo Fernhall
发表日期
2021/7
期刊
Experimental physiology
卷号
106
期号
7
页码范围
1643-1653
简介
New Findings
- What is the central question of this study?Does cerebrovascular pulsatility respond differently to acute increases in arterial stiffness in middle‐aged compared with young adults?
- What is the main finding and its importance?Compared with young adults, middle‐aged adults exhibited similar changes in cerebral pulsatile damping despite attenuated changes in carotid diameter and cerebrovascular pulsatility during blood pressure‐dependent, but not blood pressure‐independent, increases in large artery stiffness.
Abstract
Acute manipulation of arterial stiffness through interventions that increase sympathetic activity might provoke cerebral pulsatility and damping and reveal whether cerebrovascular haemodynamics respond differently to transient elevations in arterial stiffness in middle‐aged compared with young adults. We compared cerebral pulsatility and damping in middle‐aged versus young …
学术搜索中的文章
WK Lefferts, EC Lefferts, BA Hibner, KJ Smith… - Experimental physiology, 2021