作者
Catherine H Bozio, Jeni Vuong, E Kainne Dokubo, Mosoka P Fallah, Lucy A McNamara, Caelin C Potts, John Doedeh, Miatta Gbanya, Adam C Retchless, Jaymin C Patel, Thomas A Clark, Henry Kohar, Thomas Nagbe, Peter Clement, Victoria Katawera, Nuha Mahmoud, Harouna M Djingarey, Anne Perrocheau, Dhamari Naidoo, Mardia Stone, Roseline N George, Desmond Williams, Alex Gasasira, Tolbert Nyenswah, Xin Wang, LeAnne M Fox, Youhn Konway, Samson Q Wiah, Vivian Doedeh, Umaru Bao, George Senneh, Lawrence Gorwor, Philemon Gonotee, Thomas Paasewe, George Tamatai, James Yarkeh, Samuel Smith, Annette Brima-Davis, George Dauda, Thomas Monger, Leleh W Gornor-Pewu, Siafa Lombeh, Himiede W Wilson, Mark Korvayan, Nathaniel Dovillie, Ralph Jetoh, Fahn Taweh, Yatta Vera Walker, Patrick Hardy, Maxwell Freeman, Geraldine George, Garrison Kerwillain, Sylvester Toe, Emmanuel Ghartey, Lawrence Larway, Dedesco Gweh, Denise Allen, Suzanne Friesen, Gulu Gwesa, Carl Kinkade, Mulbah Reed, Arthur Chang, Josiah George, Joshua Schier, Jerry Thomas, Maureen H Diaz, Laurel T Jenkins, Barbara E Mahon, Susanna E Schmink, Sandeep J Joseph, Jessica L Waller, Melissa J Whaley, Jonas M Winchell, Ray R Arthur, Serena Fuller, Kira Christian, John T Redd, Kwuakuan DM Yealue, Jeremias Naiene, Joseph Asamoah Frimpong, Maame Amo-Addae, Olayinka Stephen, Anne Von Gottberg, Muhamed Taha
发表日期
2018/12/1
期刊
The Lancet Infectious Diseases
卷号
18
期号
12
页码范围
1360-1367
出版商
Elsevier
简介
Background
On April 25, 2017, a cluster of unexplained illnesses and deaths associated with a funeral was reported in Sinoe County, Liberia. Molecular testing identified Neisseria meningitidis serogroup C (NmC) in specimens from patients. We describe the epidemiological investigation of this cluster and metagenomic characterisation of the outbreak strain.
Methods
We collected epidemiological data from the field investigation and medical records review. Confirmed, probable, and suspected cases were defined on the basis of molecular testing and signs or symptoms of meningococcal disease. Metagenomic sequences from patient specimens were compared with 141 meningococcal isolate genomes to determine strain lineage.
Findings
28 meningococcal disease cases were identified, with dates of symptom onset from April 21 to April 30, 2017: 13 confirmed, three probable, and 12 suspected. 13 patients died. Six …
学术搜索中的文章
CH Bozio, J Vuong, EK Dokubo, MP Fallah… - The Lancet Infectious Diseases, 2018