作者
Sebastian Leschka, Sara Seitun, Matthias Dettmer, Stephan Baumüller, Paul Stolzmann, Robert Goetti, Hans Scheffel, Gudrun Feuchtner, Kathrin Wunnicke, Simon Wildermuth, Christian Oehlschlegel, Borut Marincek, Wolfram Jochum, Hatem Alkadhi
发表日期
2010/9/1
期刊
Journal of cardiovascular computed tomography
卷号
4
期号
5
页码范围
301-308
出版商
Elsevier
简介
BACKGROUND
Identification and differentiation of coronary atherosclerotic plaques may improve risk stratification for incident coronary events.
OBJECTIVE
We investigated the ability of dual-source computed tomography (CT) to depict and characterize atherosclerotic coronary plaques.
METHODS
Contrast-enhanced CT was performed in 25 human heart specimens with a total of 322 histologically determined plaques. Coronary plaques were classified on CT as (1) noncalcified, mixed, or calcified and (2) by CT attenuation values. Atherosclerotic plaques were histopathologically characterized according to the Stary classification.
RESULTS
CT detected 79% (245/322) of all plaques. Lesions missed by CT were generally early lesions, type I (n = 31), type II (n = 38), or type III (n = 8), according to Stary. CT detected 29% of early (Stary I–III) and 100% of advanced (Stary IV–VIII) plaques. Plaque classification as …
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S Leschka, S Seitun, M Dettmer, S Baumüller… - Journal of cardiovascular computed tomography, 2010