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Women 8 (33) 2 (50) 1 (20) 5 (33) Men 16 (67) 2 (50) 4 (80) 10 (67) BMI> 30, No.(%) 5 (23) 1 (50) 1 (20) 3 (20) High blood pressure, No.(%) 6 (26) 1 (25) 2 (50) 3 (20) SOFA score, mean (SD) 2.8 (0.9) 3.5 (0.7) 2.8 (0.8) 2.7 (1) Oxygen supplementation, No.(%)< 4 L/min 16 (67) 2 (50) 3 (60) 11 (73)≥ 4 L/min or HFNC 8 (33) 2 (50) 2 (40) 4 (27) Respiratory rate, mean (SD), breaths/min 18 (2.7) 18.3 (4) 20 (3.6) 17.3 (1.8) Gas exchange and VAS scores before PP PaO2, mean (SD), mm Hg 72.8 (14.2) 79.7 (11.7) 66.4 (8.9) 73.6 (15.9) PaCO2, mean (SD), mm Hg 34.1 (5.3) 39.7 (4.6) 32.4 (3.9) 33.5 (5.4) VAS, median (IQR) b

Dyspnea 3 (2-5) 3 (1-3) 5 (3-7) 2 (1-5) Discomfort 0 (0-0) 0 (0-0) 0 (0-0) 0 (0-1) Gas exchange and VAS scores during PPc PaO2, mean (SD), mm Hg 91 (27.3) 73 (12.1) 94.9 (28.3) PaCO2, mean (SD), mm Hg 32.8 (4.5) 32 (3) 33 (4.8) VAS, median (IQR) b