作者
Jean-Baptiste Beauval, Guillaume Ploussard, Michel Soulié, Christian Pfister, Simon Van Agt, Sébastien Vincendeau, Sébastien Larue, Jérome Rigaud, Nicolas Gaschignard, Morgan Rouprêt, Sarah Drouin, Mickael Peyromaure, Jean Alexandre Long, Francois Iborra, Guy Vallancien, Francois Rozet, Laurent Salomon, Members of Committee of Cancerology of the French Association of Urology (CCAFU
发表日期
2012/9/1
期刊
Urology
卷号
80
期号
3
页码范围
656-660
出版商
Elsevier
简介
OBJECTIVE
To evaluate the pathologic features of surgical specimens after radical prostatectomy in patients with low-risk prostate cancer fulfilling the strictest pathologic selection criteria for active surveillance.
METHODS
Retrospective analysis of 10 785 consecutive radical prostatectomy performed in 10 university hospitals (January 2003 through December 2008). A total of 919 patients fulfilled the following unique and very stringent criteria: T1c, prostate-specific antigen (PSA) <10 ng/mL, a single positive biopsy, tumor length <3 mm, and Gleason score <7. Clinico-biologic and pathologic data at diagnosis and after radical prostatectomy, prostatic and tumor volume, pathologic Gleason score and stage, positive surgical margins, insignificant prostate cancer, and PSA outcomes were recorded.
RESULTS
Median age was 63 years. Mean prebiopsy PSA level was 6.2 ng/mL. At radical prostatectomy, Gleason score …
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