作者
Germaine M Buck Louis, Rajeshwari Sundaram, Anne M Sweeney, Enrique F Schisterman, José Maisog, Kurunthachalam Kannan
发表日期
2014/5/1
期刊
Fertility and sterility
卷号
101
期号
5
页码范围
1359-1366
出版商
Elsevier
简介
Objective
To assess the relationship between environmental chemicals and couple fecundity or time to pregnancy (TTP).
Design
Prospective cohort.
Setting
Communities of targeted populations with reported exposure.
Patient(s)
501 couples recruited upon discontinuing contraception to become pregnant, 2005–2009.
Intervention(s)
None.
Main Outcome Measure(s)
Fecundability odds ratios (FORs) and 95% confidence intervals (CIs) estimated for each partner’s chemical concentrations adjusted for age, body mass index, cotinine, creatinine, and research site while accounting for time off contraception.
Result(s)
Couples completed interviews and anthropometric assessments and provided the urine specimens for quantification of bisphenol A (BPA) and 14 phthalate metabolites, which were measured using high-performance liquid chromatography with electrospray triple-quadrupole mass spectrometer. Women recorded …
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