作者
Guido Pastore, Ariana Znaor, Filippo Spreafico, Norbert Graf, Kathy Pritchard-Jones, Eva Steliarova-Foucher
发表日期
2006/9/1
期刊
European journal of cancer
卷号
42
期号
13
页码范围
2103-2114
出版商
Pergamon
简介
More than 5000 cases of malignant renal tumour diagnosed in children under the age of 15 years during the period 1978–1997 in Europe, were extracted from the database of the Automated Childhood Cancer Information System (ACCIS). In 1988–1997 the age-standardised incidence rate of childhood renal tumours in Europe was 8.8 per million, with significant differences between regions. Wilms’ tumour (WT, M-8960) accounted for 93% of renal tumours and about 7% were bilateral. The incidence rates of WT increased over the 20 years, by 0.7% per year. European 5-year survival for children diagnosed with WT in 1988–1997 was 85%, ranging from 73% in the East to 91% in the North. Patients in the age group 0–3 years at diagnosis had a more favourable prognosis (5-year survival 87%) than those diagnosed later (81%), P<0.0001. Patients with unilateral WT (n=2085) had better 5-year survival (85%) than …
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