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The dearth of potential of diagnostic and treatment methods hinders the fight against tumors. The advances in nanotechnology are emerging, expressing countless latent applications, whereas, the DNA damaging conventional approach of anti-cancer therapy is associated with low stability in acidic environment, untargeted release, low solubility and biocompatibility, thus establishing a dire need to develop a specific, accurate and reliable approach. Thyroid cancer is cancer of the butterfly shaped thyroid gland, which is more common to women, and is prevalent up to 43% in patients between 65 and 45 years of age. The adequacy of surgical strategies, like thyroidectomy and nutraceutical approaches are associated with certain challenges and still need to be investigated further. The progressing nanotechnology-based diagnostic methods have some advantages, like primarily faster testing and early disease …