作者
Mark Joy, FD Richard Hobbs, Jamie Lopez Bernal, Julian Sherlock, Gayatri Amirthalingam, Dylan McGagh, Oluwafunmi Akinyemi, Rachel Byford, Gavin Dabrera, Jienchi Dorward, Joanna Ellis, Filipa Ferreira, Nicholas Jones, Jason Oke, Cecilia Okusi, Brian D Nicholson, Mary Ramsay, James P Sheppard, Mary Sinnathamby, Maria Zambon, Gary Howsam, John Williams, Simon de Lusignan
发表日期
2020/12/1
期刊
British Journal of General Practice
卷号
70
期号
701
页码范围
e890-e898
出版商
British Journal of General Practice
简介
Background
The SARS-CoV-2 pandemic has passed its first peak in Europe.
Aim
To describe the mortality in England and its association with SARS-CoV-2 status and other demographic and risk factors.
Design and setting
Cross-sectional analyses of people with known SARS-CoV-2 status in the Oxford RCGP Research and Surveillance Centre (RSC) sentinel network.
Method
Pseudonymised, coded clinical data were uploaded from volunteer general practice members of this nationally representative network (n = 4 413 734). All-cause mortality was compared with national rates for 2019, using a relative survival model, reporting relative hazard ratios (RHR), and 95% confidence intervals (CI). A multivariable adjusted odds ratios (OR) analysis was conducted for those with known SARS-CoV-2 status (n = 56 628, 1.3%) including multiple imputation and inverse probability analysis, and a complete cases sensitivity …
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M Joy, FDR Hobbs, JL Bernal, J Sherlock… - British Journal of General Practice, 2020