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Faecal immunochemical testing (FIT) is recommended by the National Institute for Health and Care Excellence (NICE) to triage symptomatic primary care patients for further investigation of colorectal cancer.

To ascertain the diagnostic performance of FIT in symptomatic adult primary care patients.

Faecal samples from routine primary care practice in Oxfordshire, UK were analysed using the HM‐JACKarc FIT method between March 2017 and March 2020. Clinical details were recorded. Patients were followed for up to 36 months in linked hospital records for evidence of benign and serious (colorectal cancer, high‐risk adenomas and bowel inflammation) colorectal disease. The diagnostic accuracy of FIT is reported by gender, age group and FIT threshold.

In 9896 adult patients with at least 6‐month follow‐up, a FIT result ≥10 µg Hb/g faeces had a sensitivity for colorectal …