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Subject: The coronavirus pandemic, which began in 2019, is a global outbreak of coronavirus disease. The World Health Organization (WHO) also classified Severe Acute Respiratory Syndrome (SARS) as a new coronavirus (SARS-CoV-2). Wuhan, China, was the first place in December 2019 when the pandemic was found. LDH levels were related with a six-fold increase in the risk of developing severe COVID-19 disease. Objective of the study: Estimation of enzyme activity of Lactate Dehydrogenase enzyme (LDH) and d-dimer in patients with COVID-19 to estimate the behavior of enzyme during the period of disease. Correlation of enzyme activity Lactate Dehydrogenase (LDH) with d-dimer. More crucially, elevated LDH was related with a 16-fold increase in the risk of death. Abnormal coagulation function, including elevated D-dimer, has been demonstrated to be more common in deceased patients with COVID …