作者
Chintan S Desai, Hongyan Ning, Joseph Kang, Aaron R Folsom, Joseph F Polak, Christopher T Sibley, Russell Tracy, Donald M Lloyd-Jones
发表日期
2013/6/1
期刊
The American journal of cardiology
卷号
111
期号
11
页码范围
1541-1546
出版商
Excerpta Medica
简介
Subclinical atherosclerosis measured by coronary artery calcium (CAC) is associated with increased risk for multiple cardiovascular disease (CVD) outcomes and non-CVD death simultaneously. The aim of this study was to determine the competing risks of specific CVD events and non-CVD death associated with varying burdens of subclinical atherosclerosis. A total of 3,095 men and 3,486 women from the Multi-Ethnic Study of Atherosclerosis (MESA), aged 45 to 84 years, from 4 ethnic groups were included. Participants were stratified by CAC score (0, 1 to 99, and ≥100). Competing Cox models were used to determine competing cumulative incidences and hazard ratios within a group (e.g., those with CAC scores ≥100) and hazard ratios for specific events between groups (e.g., CAC score ≥100 vs 0). Risks were compared for specific CVD events and also against non-CVD death. In women, during a mean …
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