作者
Dan Turner, Arie Levine, Johanna C Escher, Anne M Griffiths, Richard K Russell, Axel Dignass, Jorge Amil Dias, Jiri Bronsky, Christian P Braegger, Salvatore Cucchiara, Lissy de Ridder, Ulrika L Fagerberg, Séamus Hussey, Jean-Pierre Hugot, Sanja Kolacek, Kaija Leena Kolho, Paolo Lionetti, Anders Pærregaard, Alexander Potapov, Risto Rintala, Daniela E Serban, Annamaria Staiano, Brian Sweeny, Gigi Veerman, Gabor Veres, David C Wilson, Frank M Ruemmele
发表日期
2012/9/1
期刊
Journal of pediatric gastroenterology and nutrition
卷号
55
期号
3
页码范围
340-361
出版商
LWW
简介
Methods:
A group of 27 experts in pediatric IBD participated in an iterative consensus process including 2 face-to-face meetings, following an open call to ESPGHAN and ECCO members. A list of 23 predefined questions were addressed by working subgroups based on a SR of the literature.
Results:
A total of 40 formal recommendations and 68 practice points were endorsed with a consensus rate of at least 89% regarding initial evaluation, how to monitor disease activity, the role of endoscopic evaluation, medical and surgical therapy, timing and choice of each medication, the role of combined therapy, and when to stop medications. A management flowchart, based on the Pediatric Ulcerative Colitis Activity Index (PUCAI), is presented.
Conclusions:
These guidelines provide clinically useful points to guide the management of UC in children. Taken together, the recommendations offer a standardized protocol that …
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D Turner, A Levine, JC Escher, AM Griffiths, RK Russell… - Journal of pediatric gastroenterology and nutrition, 2012