作者
Ahmet Fuat, Jeremy J Murphy, A Pali S Hungin, Jane Curry, Ali A Mehrzad, Andrew Hetherington, Jennifer I Johnston, W Stuart A Smellie, Victoria Duffy, Patricia Cawley
发表日期
2006/5/1
期刊
British Journal of General Practice
卷号
56
期号
526
页码范围
327-333
出版商
British Journal of General Practice
简介
Background
National guidelines suggest the use of natriuretic peptides in suspected heart failure but there have been no studies comparing assays in primary care.
Aim
To test and compare the diagnostic accuracy and utility of B-type natriuretic peptide (BNP) and N-terminal B-type natriuretic peptide (NT proBNP) in diagnosing heart failure due to left ventricular systolic dysfunction in patients with suspected heart failure referred by GPs to one-stop diagnostic clinics.
Design of study
Community cohort, prospective, diagnostic accuracy study.
Setting
One-stop diagnostic clinics in Darlington Memorial and Bishop Auckland General Hospitals and general practices in South Durham.
Subjects
Two hundred and ninety-seven consecutive patients with symptoms and signs suggestive of heart failure referred from general practice.
Method
The study measured sensitivity, specificity, positive and negative predictive values (PPV …
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A Fuat, JJ Murphy, APS Hungin, J Curry, AA Mehrzad… - British Journal of General Practice, 2006