作者
Jennifer Velloza, Nomhle Khoza, Fiona Scorgie, Miria Chitukuta, Prisca Mutero, Kudzai Mutiti, Nomvuyo Mangxilana, Lumka Nobula, Michelle A Bulterys, Millicent Atujuna, Sybil Hosek, Renee Heffron, Linda‐Gail Bekker, Nyaradzo Mgodi, Mike Chirenje, Connie Celum, Sinead Delany‐Moretlwe, HPTN 082 Study Group
发表日期
2020/3/1
期刊
African Journal of Reproduction and Gynaecological Endoscopy
卷号
23
期号
3
页码范围
e25463
出版商
Medknow
简介
Introduction: Stigma and disclosure concerns have been key barriers to oral pre-exposure prophylaxis (PrEP) adherence for African adolescent girls and young women (AGYW) in efficacy trials. We aimed to understand the impact of these factors among African AGYW in an open-label PrEP study.
Methods: HPTN 082 was an open-label PrEP study among AGYW (ages 16 to 24) in Harare, Zimbabwe, and Cape Town and Johannesburg, South Africa from 2016 to 2018. Women starting PrEP were randomized to standard adherence support (counselling, two-way SMS, monthly adherence clubs) or standard support plus drug-level feedback. Serial in-depth interviews were conducted among 67 AGYW after 13-week and 26-week study visits to explore experiences of stigma, disclosure and PrEP adherence. We analysed data by coding transcripts and memo-writing and diagramming to summarize themes. Results …
学术搜索中的文章
J Velloza, N Khoza, F Scorgie, M Chitukuta, P Mutero… - African Journal of Reproduction and Gynaecological …, 2020