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Globally, several health governing bodies and ministries have endorsed universal HCV prenatal screening to identify and link women into HCV-related care. There are multiple benefits to universal screening, including identifying women who are unaware of their HCV status, reducing the risk of vertical transmission, facilitating the optimal follow-up of infants, and cost-effectiveness. 2, 3 Most countries recommend riskbased HCV screening, requiring people to disclose their behaviour, such as current or past drug use. Under universal prenatal screening for HCV, health services could prompt testing without the need for pregnant women to disclose risk behaviour. HCV treatment during pregnancy, if approved, could add further benefits. The available clinical data suggest that ribavirin-free sofosbuvir-based direct-acting antiviral treatment during the third trimester is safe and efficacious, and larger clinical trials involving …