作者
Giovanni Corona, Matteo Monami, Giulia Rastrelli, Antonio Aversa, Yuliya Tishova, Farid Saad, Andrea Lenzi, Gianni Forti, Edoardo Mannucci, Mario Maggi
发表日期
2011/1
来源
The journal of sexual medicine
卷号
8
期号
1
页码范围
272-283
出版商
Oxford University Press
简介
Introduction
Metabolic syndrome (MetS) is often associated with male hypogonadism. Despite the well‐known link, the role of testosterone replacement therapy (TRT) in MetS has not been completely clarified.
Aim
To systematically analyse the relationship between androgen levels and MetS we performed a review and meta‐analyses of available prospective and cross‐sectional studies. In addition, a specific meta‐analysis on the metabolic effects of TRT in available randomized clinical trials (RCTs) was also performed.
Methods
An extensive Medline search was performed including the following words “testosterone,” “metabolic syndrome,” and “males”.
Main Outcome Measures
Out of 323 retrieved articles, 302 articles were excluded for different reasons. Among the 20 published studies included, 13, 3, and 4 were cross‐sectional …
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