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Aim: To assess the impact of septoplasty on patients with nasal obstruction secondary to deviated nasal septum based on the disease-specific quality-of-life questionnaire. Design: Prospective.

Methods: Patients undergoing septoplasty with/without turbinectomy after no clinical improvement with medical treatment were assessed by the NOSE questionnaire before and 3 months after surgery. We evaluated the surgical improvement based on total score, the magnitude of the surgery in the disease-specific quality of life and the correlation between the preoperative score and postoperatively improvement.

Results: Fourty-six patients were included in the study. There was a statistically significant improvement in the preoperative NOSE score (md= 75, IQR= 26) and after three months (md= 10, IQR= 20)(p< 0.001. T-Wilcoxon). The standardized response mean was 3.07. We found a strong correlation between the preoperative score in the NOSE questionnaire and improvements in the postoperative period (r=-0.789, p< 0.001, Spearman). No difference was found in improvement scores by gender.(p= 0.668, U-Mann-Whitney).

Conclusion: Septoplasty resulted in a statistically significant improvement in the disease-specific QOL questionnaire.