作者
Darryl P Leong, Vincent Fradet, Bobby Shayegan, Emmanuelle Duceppe, Robert Siemens, Tamim Niazi, Laurence Klotz, Ian Brown, Joseph Chin, Luke Lavallee, Negareh Mousavi, Patrick Luke, Himu Lukka, Darin Gopaul, Philippe Violette, Rob J Hamilton, Margot K Davis, Sarah Karampatos, Rajibul Mian, Guila Delouya, Yves Fradet, Som Mukherjee, David Conen, Annabel Chen-Tournoux, Christopher Johnson, Amal Bessissow, George Dresser, Adnan Kazi Hameed, Husam Abdel-Qadir, Alp Sener, Raveen Pal, PJ Devereaux, Jehonathan Pinthus
发表日期
2020/6
期刊
The Journal of urology
卷号
203
期号
6
页码范围
1109-1116
出版商
Wolters Kluwer
简介
Purpose
We describe the cardiovascular risk profile in a representative cohort of patients with prostate cancer treated with or without androgen deprivation therapy.
Materials and Methods
We prospectively characterized in detail 2,492 consecutive men (mean age 68 years) with prostate cancer (newly diagnosed or with a plan to prescribe androgen deprivation therapy for the first time) from 16 Canadian sites. Cardiovascular risk was estimated by calculating Framingham risk scores.
Results
Most men (92%) had new prostate cancer (intermediate risk 41%, high risk 50%). The highest level of education achieved was primary school in 12%. Most (58%) were current or former smokers, 22% had known cardiovascular disease, 16% diabetes, 45% hypertension, 31% body mass index 30 kg/m2 or greater, 24% low levels of physical activity, mean handgrip strength was 37.3 kg and 69% had a Framingham risk score …
学术搜索中的文章
DP Leong, V Fradet, B Shayegan, E Duceppe… - The Journal of urology, 2020