作者
Ali Afshar-Oromieh, Eleni Avtzi, Frederik L Giesel, Tim Holland-Letz, Heinz G Linhart, Matthias Eder, Michael Eisenhut, Silvan Boxler, Boris A Hadaschik, Clemens Kratochwil, Wilko Weichert, Klaus Kopka, Jürgen Debus, Uwe Haberkorn
发表日期
2015/2
期刊
European journal of nuclear medicine and molecular imaging
卷号
42
页码范围
197-209
出版商
Springer Berlin Heidelberg
简介
Purpose
Since the introduction of positron emission tomography (PET) imaging with 68Ga-PSMA-HBED-CC (=68Ga-DKFZ-PSMA-11), this method has been regarded as a significant step forward in the diagnosis of recurrent prostate cancer (PCa). However, published data exist for small patient cohorts only. The aim of this evaluation was to analyse the diagnostic value of 68Ga-PSMA-ligand PET/CT in a large cohort and the influence of several possibly interacting variables.
Methods
We performed a retrospective analysis in 319 patients who underwent 68Ga-PSMA-ligand PET/CT from 2011 to 2014. Potential influences of several factors such as prostate-specific antigen (PSA) level and doubling time (DT), Gleason score (GSC), androgen deprivation therapy (ADT), age and amount of injected tracer were evaluated. Histological verification was …
学术搜索中的文章
A Afshar-Oromieh, E Avtzi, FL Giesel, T Holland-Letz… - European journal of nuclear medicine and molecular …, 2015
