作者
Lourdes Ibánez, Giorgia Sebastiani, Abel Lopez-Bermejo, Marta Díaz, Maria Dolores Gomez-Roig, Francis de Zegher
发表日期
2008/7/1
期刊
The Journal of Clinical Endocrinology & Metabolism
卷号
93
期号
7
页码范围
2774-2778
出版商
Oxford University Press
简介
Context: Fetal development is thought to be gender specific for adiposity and circulating insulin and IGF-I but not adipokinemia, as judged by serum visfatin and adiponectin at term birth. We studied the potential relationship between these gender specificities and fetal growth.
Setting: The study was conducted at a university hospital.
Study Population: Subjects included 96 strictly matched neonates born appropriate for gestational age (AGA; 24 girls, 24 boys) or small for gestational age (SGA; 24 girls, 24 boys).
Main Outcomes: Outcomes included serum insulin, IGF-I, visfatin, total and high-molecular-weight (HMW) adiponectin, osteocalcin at term birth, and neonatal body composition by absorptiometry.
Results: Cord insulin and IGF-I levels were higher in girls than boys (P ≤ 0.01), in both the AGA and SGA subpopulation. In AGA newborns, fat and lean mass …
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