作者
Jaime Mendiola, Niels Jørgensen, Anna-Maria Andersson, Antonia M Calafat, Xiaoyun Ye, J Bruce Redmon, Erma Z Drobnis, Christina Wang, Amy Sparks, Sally W Thurston, Fan Liu, Shanna H Swan
发表日期
2010/9
期刊
Environmental health perspectives
卷号
118
期号
9
页码范围
1286-1291
出版商
National Institute of Environmental Health Sciences
简介
Background
Rodent and in vitro studies have demonstrated the estrogenicity of bisphenol A (BPA). However, few studies have examined the relationship between human exposure to BPA and male reproductive function.
Objectives
We investigated the relationships between environmental BPA exposure and reproductive parameters, including semen quality and male reproductive hormones, in prospectively recruited fertile men.
Methods
Participants (n = 375) were partners of pregnant women who participated in the Study for Future Families in four U.S. cities, and all of the men provided blood, semen, and urine samples. BPA was measured in urine. Serum samples were analyzed for reproductive hormones, including follicle-stimulating hormone, luteinizing hormone (LH), testosterone, inhibin B, estradiol, and sex hormone–binding globulin (SHBG), as well as the free androgen index (FAI). Semen analyses were …
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