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Liposarcomas are most common soft tissue sarcomas usually seen in deep soft tissues of extremities and retroperitoneum. Although secondary involvement of gastrointestinal system can occur in cases of retroperitoneal tumours, liposarcomas primarily involving the gastrointestinal tract are extremely uncommon. Intusussception refers to telescoping of contiguous segments of intestine causing obstruction. Colo-colic intusussception is rare in adults and usually associated with a malignant etiology, usually epithelial malignancies (adenocarcinomas).

Colonic liposarcomas leading to colo-colic intussusception are extremely rare, with only six cases reported in the literature.

In this report, we describe this rare occurrence in a 66-year-old lady and highlight the diagnostic difficulties such …